منابع مشابه
Pharmacokinetics of Rifampicin
founder [5]. We controlled for the significant differences between groups by adjusting for the correspondents’ variables in the multivariable analysis and treating the confounding through purposeful selection method [3]. If we consider hospitalization for pneumonia, the adjusted hazard ratio (HR) decreased when the 2 covariates history of hospitalization for pneumonia and number of outpatient v...
متن کاملClinical Pharmacokinetics of Rifampicin in Patients With
BIOCHEMICAL AND IMMUNOLOGICAL PARAMETERS 3 Medellín-Garibay SE1, Cortez-Espinosa N1, Milán-Segovia RC1, Magaña-Aquino M2, 4 Vargas-Morales JM1, González-Amaro R3, Portales-Pérez DP1, Romano-Moreno S1#. 5 1Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, San Luis 6 Potosí, México; 2Hospital Central “Dr. Ignacio Morones Prieto”, San Luis Potosí, 7 México; 3Facultad de Medic...
متن کاملPharmacokinetics of isoniazid, rifampicin, pyrazinamide and ethambutol in Indian children
BACKGROUND The available pharmacokinetic data on anti-tubercular drugs in children raises the concern of suboptimal plasma concentrations attained when doses extrapolated from adult studies are used. Also, there is lack of consensus regarding the effect of malnutrition on pharmacokinetics of anti-tubercular drugs in children. We conducted this study with the aims of determining the plasma conce...
متن کاملEffect of Rifampicin on the Pharmacokinetics of Lenvatinib in Healthy Adults
BACKGROUND AND OBJECTIVES Lenvatinib is an oral, multitargeted tyrosine kinase inhibitor under clinical investigation in solid tumours. This study evaluated the influence of P-glycoprotein (P-gp) inhibition (single-dose rifampicin) and simultaneous cytochrome P450 3A4 (CYP3A4)/P-gp induction (multiple-dose rifampicin) on lenvatinib pharmacokinetics. METHODS This Phase I, single-centre, single...
متن کاملEffect of rifampicin & isoniazid on the steady state pharmacokinetics of moxifloxacin
BACKGROUND & OBJECTIVES Moxifloxacin (MFX) is reported to have promising antimycobacterial activity, and has a potential to shorten tuberculosis (TB) treatment. We undertook this study to examine the influence of rifampicin (RMP) and isoniazid (INH) on the steady state pharmacokinetics of MFX individually in healthy individuals. METHODS A baseline pharmacokinetic study of MFX (400 mg once dai...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2007
ISSN: 1058-4838,1537-6591
DOI: 10.1086/511081